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KMID : 0869619950120010023
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Journal of Korean Society of Hospital Pharmacists
1995 Volume.12 No. 1 p.23 ~ p.27
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Current Trend of microorganisms and their antimicrobial Resistance profile at St. Mary´s Hospital
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김숙희/Kim, Sook Hee
김옥녀/유진홍/신완식/Kim, Ok Nyu/Yoo, Jin Hong/Shin, Wan Shik
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Abstract
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The emerging antimicrobial resistance is providing an important impact on nosocomial infection. Judicious use of antimicrobial agents is one of the effective control measures for the prevention of it. Therefore, we analysed the usage pattern of antimicrobial agents and the antimicrobial resistance profile.
1. The major isolates were S.aureus(15%0, E.coli(13%),, P.aeruginosa(12%), K.pneumoniae(6%) and X.maltophilia(6%).
2. The most frequently used oral antimicrobials were quinolones(44%), cephalosporins(38%) and penicillins(10%).
3. The cephalosporin(47%) was the most frequently used parenteral agent, followed by aminoglycosides(28%) and penicillins(15%).
4. Over 2/3 of S.aureus were resistant to all β-lactams including oxacillin.
5. E.coli was highly susceptible to amikacin, imipenem and ceftriaxone.
6. P.aeruginosa represented a very low level resistance to imipenem and ceftazidime.
7. K.pneumoniae showed a high susceptibility to the almost all antimicrobials.
8. X.maltophilia was resistant to various antimicrobials.
9. MRSA(methicillin resistant Staphylococcus aureus) showed high prevalence and it imposes a major threat to the nosocomial infection.
In conclusion, current isolated microorganisms were resistant to commonly used antimicrobial agents especially cephalosporins and quinolones. It is important do more intensive surveillance of antimicrobial usage and microbiological monitoring.
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KEYWORD
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